Reactome | deamination of 2'-Deoxycytidine to 2'-Deoxyuridine

Schema > Reaction > Entries

deamination of 2'-Deoxycytidine to 2'-Deoxyuridine Show undefined attributes

catalystActivity	[CatalystActivity:10563228] cytidine deaminase activity of CDA tetramer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10563230
displayName	deamination of 2'-Deoxycytidine to 2'-Deoxyuridine
eventOf	[Pathway:R-DRE-73614] Pyrimidine salvage - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-74376] (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) - Danio rerio
inferredFrom	[Reaction:R-HSA-73608] deamination of 2'-Deoxycytidine to 2'-Deoxyuridine - Homo sapiens
input	[DefinedSet:R-ALL-500829] Cyt-Rib, dC [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	deamination of 2'-Deoxycytidine to 2'-Deoxyuridine cytidine + H2O + H(+) => uridine + NH4(+) 2'-deoxycytidine + H2O + H(+) => 2'-deoxyuridine + NH4(+) (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)
output	[DefinedSet:R-ALL-500430] (d)Ura [cytosol] [SimpleEntity:R-ALL-31633] NH4+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-73608
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-73614] Pyrimidine salvage
(precedingEvent)	[Reaction:R-DRE-74376] (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP)
(inferredTo)	[Reaction:R-HSA-73608] deamination of 2'-Deoxycytidine to 2'-Deoxyuridine

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