Reactome | 60S ribosomal complex [cytosol]

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60S ribosomal complex [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DRE-9948416] VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] - Danio rerio [Complex:R-DRE-9948361] LTN1:TCF25:NEMF:60S ribosomal subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] - Danio rerio
consumedByEvent	[Reaction:R-DRE-156826] Dissociation of L13a from the 60s ribosomal subunit - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10563100
displayName	60S ribosomal complex [cytosol]
hasComponent	[GenomeEncodedEntity:R-DRE-72498] Ghost homologue of 28S rRNA [cytosol] [GenomeEncodedEntity:R-DRE-72496] Ghost homologue of 5.8S rRNA [cytosol] [GenomeEncodedEntity:R-DRE-72494] Ghost homologue of 5S rRNA [cytosol] [GenomeEncodedEntity:R-DRE-72442] Ghost homologue of RPL27A [cytosol] [GenomeEncodedEntity:R-DRE-72466] Ghost homologue of RPL37 [cytosol] [GenomeEncodedEntity:R-DRE-72468] Ghost homologue of RPL37A [cytosol] [GenomeEncodedEntity:R-DRE-72478] Ghost homologue of RPL41 [cytosol] [GenomeEncodedEntity:R-DRE-72492] Ghost homologue of RPL9 [cytosol] [EntityWithAccessionedSequence:R-DRE-72402] rpl10 [cytosol] [EntityWithAccessionedSequence:R-DRE-72404] rpl10a [cytosol] [EntityWithAccessionedSequence:R-DRE-72406] rpl11 [cytosol] [EntityWithAccessionedSequence:R-DRE-72408] rpl12 [cytosol] [EntityWithAccessionedSequence:R-DRE-72410] rpl13 [cytosol] [EntityWithAccessionedSequence:R-DRE-72412] rpl13a [cytosol] [EntityWithAccessionedSequence:R-DRE-72414] rpl14 [cytosol] [EntityWithAccessionedSequence:R-DRE-72416] RPL15 [cytosol] [EntityWithAccessionedSequence:R-DRE-72418] rpl17 [cytosol] [EntityWithAccessionedSequence:R-DRE-72420] rpl18 [cytosol] [EntityWithAccessionedSequence:R-DRE-72422] rpl18a [cytosol] [EntityWithAccessionedSequence:R-DRE-72424] rpl19 [cytosol] [EntityWithAccessionedSequence:R-DRE-72426] rpl21 [cytosol] [CandidateSet:R-DRE-8868847] RPL22,RPL22L1 [cytosol] [EntityWithAccessionedSequence:R-DRE-72430] rpl23 [cytosol] [EntityWithAccessionedSequence:R-DRE-72432] rpl23a [cytosol] [EntityWithAccessionedSequence:R-DRE-72434] rpl24 [cytosol] [EntityWithAccessionedSequence:R-DRE-72436] rpl26 [cytosol] [EntityWithAccessionedSequence:R-DRE-72440] rpl27 [cytosol] [EntityWithAccessionedSequence:R-DRE-72444] rpl28 [cytosol] [EntityWithAccessionedSequence:R-DRE-72446] RPL29 [cytosol] [EntityWithAccessionedSequence:R-DRE-72448] rpl3 [cytosol] [EntityWithAccessionedSequence:R-DRE-72452] rpl30 [cytosol] [EntityWithAccessionedSequence:R-DRE-72454] rpl31 [cytosol] [EntityWithAccessionedSequence:R-DRE-72456] RPL32 [cytosol] [EntityWithAccessionedSequence:R-DRE-72458] rpl34 [cytosol] [EntityWithAccessionedSequence:R-DRE-72460] rpl35 [cytosol] [EntityWithAccessionedSequence:R-DRE-72462] rpl35a [cytosol] [EntityWithAccessionedSequence:R-DRE-72464] rpl36 [cytosol] [EntityWithAccessionedSequence:R-DRE-72480] rpl36a [cytosol] [EntityWithAccessionedSequence:R-DRE-72470] rpl38 [cytosol] [EntityWithAccessionedSequence:R-DRE-72472] rpl39 [cytosol] [EntityWithAccessionedSequence:R-DRE-72474] rpl4 [cytosol] [EntityWithAccessionedSequence:R-DRE-72482] rpl5b [cytosol] [EntityWithAccessionedSequence:R-DRE-72484] rpl6 [cytosol] [EntityWithAccessionedSequence:R-DRE-72486] rpl7 [cytosol] [EntityWithAccessionedSequence:R-DRE-72488] rpl7a [cytosol] [EntityWithAccessionedSequence:R-DRE-72490] rpl8 [cytosol] [EntityWithAccessionedSequence:R-DRE-72396] rplp0 [cytosol] [EntityWithAccessionedSequence:R-DRE-72398] rplp1 [cytosol] [EntityWithAccessionedSequence:R-DRE-72400] rplp2b [cytosol] [EntityWithAccessionedSequence:R-DRE-72476] ubc [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-72499] 60S ribosomal complex [cytosol] - Homo sapiens
maxDepth	3
name	60S ribosomal complex
producedByEvent	[BlackBoxEvent:R-DRE-6791218] 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA - Danio rerio [Reaction:R-DRE-72673] Release of 40S and 60S subunits from the 80S ribosome - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-72499
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(hasComponent)	[Complex:R-DRE-9948416] VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] [Complex:R-DRE-9948361] LTN1:TCF25:NEMF:60S ribosomal subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] [Complex:R-DRE-9948294] 60S ribosomal subunit:peptidyl-tRNA with nascent peptide [cytosol] [Complex:R-DRE-9948303] K63polyUb-80S ribosome [cytosol] [Complex:R-DRE-9948455] LTN1:TCF25:NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala [cytosol] [Complex:R-DRE-9948304] NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala [cytosol] [Complex:R-DRE-72500] 80S ribosome [cytosol]
(input)	[Reaction:R-DRE-156826] Dissociation of L13a from the 60s ribosomal subunit
(output)	[BlackBoxEvent:R-DRE-6791218] 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA [Reaction:R-DRE-72673] Release of 40S and 60S subunits from the 80S ribosome
(inferredTo)	[Complex:R-HSA-72499] 60S ribosomal complex [cytosol]

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