Reactome | Keratin type I binds keratin type II

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10627387
displayName	Keratin type I binds keratin type II
eventOf	[Pathway:R-DRE-6805567] Keratinization - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-6805573] Keratin type I/type II heterodimers form tetramers - Danio rerio
inferredFrom	[Reaction:R-HSA-6805546] Keratin type I binds keratin type II - Homo sapiens
input	[DefinedSet:R-DRE-6809600] Keratin type I [cytosol] [DefinedSet:R-DRE-6809612] Keratin type II [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Keratin type I binds keratin type II
output	[Complex:R-DRE-6809611] Keratin heterodimer [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-6805546
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-6805567] Keratinization
(precedingEvent)	[Reaction:R-DRE-6805573] Keratin type I/type II heterodimers form tetramers
(inferredTo)	[Reaction:R-HSA-6805546] Keratin type I binds keratin type II

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