Reactome | PGLYRP3,4 binds bacterial peptidoglycan

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PGLYRP3,4 binds bacterial peptidoglycan Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10625433
displayName	PGLYRP3,4 binds bacterial peptidoglycan
eventOf	[Pathway:R-DRE-6803157] Antimicrobial peptides - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6799959] PGLYRP3,4 binds bacterial peptidoglycan - Homo sapiens
input	[SimpleEntity:R-ALL-6789198] GlcNac-(1-->4)MurNAc-L-Ala-gamma-D-Glu-L-Lys-(D-Ala)2 [peptidoglycan-based cell wall] [CandidateSet:R-DRE-6799960] PGLYRP3,4 dimers [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	PGLYRP3,4 binds bacterial peptidoglycan
output	[Complex:R-DRE-6799966] PGLYRP3,4 dimer:peptidoglycan [extracellular region]
regulatedBy	[Requirement:R-HSA-159017] Requirement by 'Zn2+ [extracellular region]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-6799959
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-6803157] Antimicrobial peptides
(inferredTo)	[Reaction:R-HSA-6799959] PGLYRP3,4 binds bacterial peptidoglycan

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