Reactome | GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P

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GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P Show undefined attributes

catalystActivity	[CatalystActivity:10625399] glucosamine-6-phosphate deaminase activity of GNPDA1,2 hexamers [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10625401
displayName	GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P
eventOf	[Pathway:R-DRE-70171] Glycolysis - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-70467] PFK tetramer phosphorylates Fru(6)P - Danio rerio
goBiologicalProcess	[GO_BiologicalProcess:14877] glucosamine catabolic process
inferredFrom	[Reaction:R-HSA-6799604] GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P - Homo sapiens
input	[SimpleEntity:R-ALL-449701] GlcN6P [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P
output	[SimpleEntity:R-ALL-29512] Fru(6)P [cytosol] [SimpleEntity:R-ALL-31633] NH4+ [cytosol]
precedingEvent	[Reaction:R-DRE-6803789] AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA - Danio rerio [Reaction:R-DRE-449715] GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-6799604
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-70171] Glycolysis
(precedingEvent)	[Reaction:R-DRE-70467] PFK tetramer phosphorylates Fru(6)P
(inferredTo)	[Reaction:R-HSA-6799604] GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P

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