Reactome | ATP13A2 transports cations from cytosol to lysosomal lumen

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ATP13A2 transports cations from cytosol to lysosomal lumen Show undefined attributes

catalystActivity	[CatalystActivity:10619301] ATPase-coupled monoatomic cation transmembrane transporter activity of ATP13A2 [lysosomal lumen]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:161320] lysosomal lumen [Compartment:17938] lysosomal membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10619303
displayName	ATP13A2 transports cations from cytosol to lysosomal lumen
eventOf	[Pathway:R-DRE-936837] Ion transport by P-type ATPases - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5692480] ATP13A2 transports cations from cytosol to lysosomal lumen - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-5692450] cation [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ATP13A2 transports cations from cytosol to lysosomal lumen
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-5692484] cation [lysosomal lumen] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-5692480
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-936837] Ion transport by P-type ATPases
(inferredTo)	[Reaction:R-HSA-5692480] ATP13A2 transports cations from cytosol to lysosomal lumen

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