Reactome | Metalloprotease DUBs

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10650118
displayName	Metalloprotease DUBs
eventOf	[Pathway:R-DRE-5688426] Deubiquitination - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-5691381] MYSM1 deubiquitinates Histone H2A - Danio rerio [Reaction:R-DRE-5691431] PSMD14 cleaves K63-linked ubiquitin - Danio rerio [Reaction:R-DRE-5691439] BRISC complex deubiquitinates NLRP3 - Danio rerio [Reaction:R-DRE-5693061] STAMBP binds STAM - Danio rerio
inferredFrom	[Pathway:R-HSA-5689901] Metalloprotease DUBs - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Metalloprotease DUBs
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-5689901
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-5688426] Deubiquitination
(inferredTo)	[Pathway:R-HSA-5689901] Metalloprotease DUBs