Reactome | Josephin domain DUBs

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Josephin domain DUBs Show undefined attributes

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10650102
displayName	Josephin domain DUBs
eventOf	[Pathway:R-DRE-5688426] Deubiquitination - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-5688797] ATXN3 family cleave Ub chains - Danio rerio [Reaction:R-DRE-5688786] ATXN3 binds RAD23 - Danio rerio [Reaction:R-DRE-5688834] ATXN3 binds VCP - Danio rerio [Reaction:R-DRE-5689111] PARK2 autoubiquitinates - Danio rerio [Reaction:R-DRE-5689085] ATXN3 binds polyUb-PARK2 - Danio rerio [Reaction:R-DRE-5688837] ATXN3 deubiquitinates polyUb-PARK2 - Danio rerio
inferredFrom	[Pathway:R-HSA-5689877] Josephin domain DUBs - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Josephin domain DUBs
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-5689877
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-5688426] Deubiquitination
(inferredTo)	[Pathway:R-HSA-5689877] Josephin domain DUBs

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