Reactome | PALM-C100-CKAP4 binds SFTPAs

Schema > Reaction > Entries

PALM-C100-CKAP4 binds SFTPAs Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10617455
displayName	PALM-C100-CKAP4 binds SFTPAs
eventOf	[Pathway:R-DRE-5683826] Surfactant metabolism - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-DRE-5686286] PALM-C100-CKAP4 transports SFTPAs from extracellular region to lamellar body - Danio rerio
inferredFrom	[Reaction:R-HSA-5686301] PALM-C100-CKAP4 binds SFTPAs - Homo sapiens
input	[EntityWithAccessionedSequence:R-DRE-5686280] ckap4 [plasma membrane] [Complex:R-DRE-5686234] SFTPA1 18mer [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	PALM-C100-CKAP4 binds SFTPAs
output	[Complex:R-DRE-5686288] PALM-C100-CKAP4:SFTPAs [plasma membrane]
precedingEvent	[Reaction:R-DRE-5686304] ZDHHC2 transfers PALM from PALM-CoA to CKAP4 - Danio rerio [BlackBoxEvent:R-DRE-5685649] SFTPAs translocate from ER membrane to extracellular region - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-5686301
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-5683826] Surfactant metabolism
(precedingEvent)	[BlackBoxEvent:R-DRE-5686286] PALM-C100-CKAP4 transports SFTPAs from extracellular region to lamellar body
(inferredTo)	[Reaction:R-HSA-5686301] PALM-C100-CKAP4 binds SFTPAs