Reactome | RHOA:GTP binds RHPN1 or RHPN2

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10615635
displayName	RHOA:GTP binds RHPN1 or RHPN2
eventOf	[Pathway:R-DRE-5666185] RHO GTPases Activate Rhotekin and Rhophilins - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5667008] RHOA:GTP binds RHPN1 or RHPN2 - Homo sapiens
input	[Complex:R-DRE-5665993] RHOA:GTP [plasma membrane] [EntityWithAccessionedSequence:R-DRE-5667007] rhpn2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	RHOA:GTP binds RHPN1 or RHPN2
output	[Complex:R-DRE-5667010] RHOA:GTP:RHPN1,RHPN2 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-5667008
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-5666185] RHO GTPases Activate Rhotekin and Rhophilins
(inferredTo)	[Reaction:R-HSA-5667008] RHOA:GTP binds RHPN1 or RHPN2

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