Reactome | Signaling by FGFR4

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10648508
displayName	Signaling by FGFR4
eventOf	[Pathway:R-DRE-190236] Signaling by FGFR - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:24611] fibroblast growth factor receptor signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DRE-190322] FGFR4 ligand binding and activation - Danio rerio [Pathway:R-DRE-5654716] Downstream signaling of activated FGFR4 - Danio rerio [Pathway:R-DRE-5654733] Negative regulation of FGFR4 signaling - Danio rerio
inferredFrom	[Pathway:R-HSA-5654743] Signaling by FGFR4 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Signaling by FGFR4 Fibroblast Growth Factor Receptor (FGFR) signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-5654743
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEncapsulatedEvent)	[Pathway:R-DRE-5673001] RAF/MAP kinase cascade
(hasEvent)	[Pathway:R-DRE-190236] Signaling by FGFR
(inferredTo)	[Pathway:R-HSA-5654743] Signaling by FGFR4

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