Reactome | Activated FGFR1:p-SHC1:GRB2:SOS1 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10615031] guanyl-nucleotide exchange factor activity of Activated FGFR1:p-SHC1:GRB2:SOS1 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10615028
displayName	Activated FGFR1:p-SHC1:GRB2:SOS1 [plasma membrane]
hasComponent	[Complex:R-DRE-5654273] Activated FGFR1:p-SHC1 [plasma membrane] [Complex:R-DRE-109797] GRB2-1:SOS1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-5654275] Activated FGFR1:p-SHC1:GRB2:SOS1 [plasma membrane] - Homo sapiens
maxDepth	9
memberOf	[DefinedSet:R-DRE-5672601] RAS GEFs [plasma membrane] - Danio rerio
name	Activated FGFR1:p-SHC1:GRB2:SOS1
producedByEvent	[Reaction:R-DRE-5654597] Activated FGFR1:p-SHC1 binds GRB2:SOS1 - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-5654275
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10615031] guanyl-nucleotide exchange factor activity of Activated FGFR1:p-SHC1:GRB2:SOS1 [plasma membrane]
(output)	[Reaction:R-DRE-5654597] Activated FGFR1:p-SHC1 binds GRB2:SOS1
(hasMember)	[DefinedSet:R-DRE-5672601] RAS GEFs [plasma membrane]
(inferredTo)	[Complex:R-HSA-5654275] Activated FGFR1:p-SHC1:GRB2:SOS1 [plasma membrane]

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