Reactome | RP2 activates the GTPase activity of ARL3

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RP2 activates the GTPase activity of ARL3 Show undefined attributes

catalystActivity	[CatalystActivity:10614271] GTPase activator activity of RP2 [cilium]
category	transition
compartment	[Compartment:18730] cilium
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10614273
displayName	RP2 activates the GTPase activity of ARL3
eventOf	[Pathway:R-DRE-5624138] Trafficking of myristoylated proteins to the cilium - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-5638006] ARL3 hydrolyzes GTP - Danio rerio
inferredFrom	[Reaction:R-HSA-5638007] RP2 activates the GTPase activity of ARL3 - Homo sapiens
input	[Complex:R-DRE-5637985] RP2:ARL3:GTP:UNC119B [cilium]
isInDisease	false
isInferred	true
maxDepth	1
name	RP2 activates the GTPase activity of ARL3
output	[Complex:R-DRE-5637985] RP2:ARL3:GTP:UNC119B [cilium]
precedingEvent	[Reaction:R-DRE-5638004] RP2 binds ARL3:GTP:UNC119B - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-5638007
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-5624138] Trafficking of myristoylated proteins to the cilium
(precedingEvent)	[Reaction:R-DRE-5638006] ARL3 hydrolyzes GTP
(inferredTo)	[Reaction:R-HSA-5638007] RP2 activates the GTPase activity of ARL3

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