Reactome | TNF-?:TNFR1 binds NSMAF

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TNF-?:TNFR1 binds NSMAF Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10613945
displayName	TNF-?:TNFR1 binds NSMAF
eventOf	[Pathway:R-DRE-5626978] TNFR1-mediated ceramide production - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-5626982] TNF-?:TNFR1:NSMAF binds RACK1 - Danio rerio
inferredFrom	[Reaction:R-HSA-5626988] TNF-?:TNFR1 binds NSMAF - Homo sapiens
input	[EntityWithAccessionedSequence:R-DRE-5626992] nsmaf [cytosol] [DefinedSet:R-DRE-3371401] TNF-? trimer:TNFR1 trimer [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	TNF-?:TNFR1 binds NSMAF
output	[Complex:R-DRE-5626996] TNF-?:TNFR1:NSMAF [plasma membrane]
precedingEvent	[Reaction:R-DRE-83660] Membrane-anchored TNF-? binds TNFR1 - Danio rerio [Reaction:R-DRE-3371353] Soluble TNF-? binds TNFR1 - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-5626988
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-5626978] TNFR1-mediated ceramide production
(precedingEvent)	[Reaction:R-DRE-5626982] TNF-?:TNFR1:NSMAF binds RACK1
(inferredTo)	[Reaction:R-HSA-5626988] TNF-?:TNFR1 binds NSMAF