Reactome | CYP2A13 oxidises AFM1 to AFM1E

Schema > Reaction > Entries

CYP2A13 oxidises AFM1 to AFM1E Show undefined attributes

catalystActivity	[CatalystActivity:10612692] monooxygenase activity of CYP2A13 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10612694
displayName	CYP2A13 oxidises AFM1 to AFM1E
eventOf	[Pathway:R-DRE-5423646] Aflatoxin activation and detoxification - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5423647] CYP2A13 oxidises AFM1 to AFM1E - Homo sapiens
input	[SimpleEntity:R-ALL-5423629] AFM1 [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	CYP2A13 oxidises AFM1 to AFM1E
output	[SimpleEntity:R-ALL-5423657] AFM1E [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
precedingEvent	[Reaction:R-DRE-5423678] CYP1A2 hydroxylates AFB1 to AFM1 - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-5423647
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-5423646] Aflatoxin activation and detoxification
(inferredTo)	[Reaction:R-HSA-5423647] CYP2A13 oxidises AFM1 to AFM1E