Reactome | Cis-homodimerization of nectins

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10586020
displayName	Cis-homodimerization of nectins
eventOf	[Pathway:R-DRE-418990] Adherens junctions interactions - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-419011] Transhomodimerization of Nectins - Danio rerio
inferredFrom	[Reaction:R-HSA-433711] Cis-homodimerization of nectins - Homo sapiens
input	2 × [DefinedSet:R-DRE-419017] Nectin [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Cis-homodimerization of nectins
output	[Complex:R-DRE-433730] Nectin cis-homodimer [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-433711
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-418990] Adherens junctions interactions
(precedingEvent)	[Reaction:R-DRE-419011] Transhomodimerization of Nectins
(inferredTo)	[Reaction:R-HSA-433711] Cis-homodimerization of nectins

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