Reactome | Nectin/Necl trans heterodimerization

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Nectin/Necl trans heterodimerization Show undefined attributes

compartment	[Compartment:204883] cell junction
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10649084
displayName	Nectin/Necl trans heterodimerization
eventOf	[Pathway:R-DRE-418990] Adherens junctions interactions - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-420580] Nectin-1:PVRL3 trans heterodimer formation - Danio rerio [Reaction:R-DRE-420598] Nectin-1:Nectin-4 trans heterodimer formation - Danio rerio [Reaction:R-DRE-420595] Necl-2:Nectin 3 trans heterodimer interaction - Danio rerio [Reaction:R-DRE-420593] PVR:PVRL3 trans heterodimer interaction - Danio rerio
inferredFrom	[Pathway:R-HSA-420597] Nectin/Necl trans heterodimerization - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Nectin/Necl trans heterodimerization
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-420597
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-418990] Adherens junctions interactions
(inferredTo)	[Pathway:R-HSA-420597] Nectin/Necl trans heterodimerization

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