Reactome | LUM (lumican) binds integrin alpha2beta1

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10608530
displayName	LUM (lumican) binds integrin alpha2beta1
eventOf	[Pathway:R-DRE-216083] Integrin cell surface interactions - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-4085133] LUM (lumican) binds integrin alpha2beta1 - Homo sapiens
input	[Complex:R-DRE-114561] ITGA2:ITGB1 [plasma membrane] [EntityWithAccessionedSequence:R-DRE-2466189] lum [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	LUM (lumican) binds integrin alpha2beta1
output	[Complex:R-DRE-4086102] LUM:Integrin alpha2beta1 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-4085133
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-216083] Integrin cell surface interactions
(inferredTo)	[Reaction:R-HSA-4085133] LUM (lumican) binds integrin alpha2beta1

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