Reactome | ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link)

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ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) Show undefined attributes

catalystActivity	[CatalystActivity:10608489] beta-galactoside alpha-2,6-sialyltransferase activity of ST6GAL1,2 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10608491
displayName	ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link)
eventOf	[Pathway:R-DRE-4085001] Sialic acid metabolism - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-4085033] ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) - Homo sapiens
input	[SimpleEntity:R-ALL-727815] CMP-Neu5Ac [Golgi lumen] [SimpleEntity:R-ALL-4086285] Gal-R [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link)
output	[SimpleEntity:R-ALL-727810] CMP [Golgi lumen] [SimpleEntity:R-ALL-4086294] Neu5Ac-2,6-Gal-R [Golgi lumen]
precedingEvent	[Reaction:R-DRE-727807] SLC35A1 exchanges CMP-Neu5Ac for CMP - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-4085033
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-4085001] Sialic acid metabolism
(inferredTo)	[Reaction:R-HSA-4085033] ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link)

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