Reactome | Nitric oxide stimulates guanylate cyclase

Schema > Pathway > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10649058
displayName	Nitric oxide stimulates guanylate cyclase
eventOf	[Pathway:R-DRE-418346] Platelet homeostasis - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-418436] Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) - Danio rerio [Pathway:R-DRE-418457] cGMP effects - Danio rerio
inferredFrom	[Pathway:R-HSA-392154] Nitric oxide stimulates guanylate cyclase - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Nitric oxide stimulates guanylate cyclase
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-392154
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-418346] Platelet homeostasis
(inferredTo)	[Pathway:R-HSA-392154] Nitric oxide stimulates guanylate cyclase

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