Reactome | DAAM1 recruits GTP-bound RHOA

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10607975
displayName	DAAM1 recruits GTP-bound RHOA
eventOf	[Pathway:R-DRE-4086400] PCP/CE pathway - Danio rerio [Pathway:R-DRE-5663220] RHO GTPases Activate Formins - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-3858495] DAAM1 recruits GTP-bound RHOA - Homo sapiens
input	[Complex:R-DRE-3858472] ppDVL:DAAM1 [cytosol] [Complex:R-DRE-3858473] RHOA:GTP:Mg2+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	DAAM1 recruits GTP-bound RHOA
output	[Complex:R-DRE-3858474] ppDVL:DAAM1:RHOA:GTP [cytosol]
precedingEvent	[Reaction:R-DRE-3858489] ppDVL binds DAAM1 - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-3858495
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-5663220] RHO GTPases Activate Formins [Pathway:R-DRE-4086400] PCP/CE pathway
(inferredTo)	[Reaction:R-HSA-3858495] DAAM1 recruits GTP-bound RHOA

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