Reactome | HSF1-dependent transactivation

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HSF1-dependent transactivation Show undefined attributes

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10649814
displayName	HSF1-dependent transactivation
eventOf	[Pathway:R-DRE-3371556] Cellular response to heat stress - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:2133281] regulation of cellular response to heat
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-5082405] Phosphorylation of HSF1 at Ser326 induces transactivation - Danio rerio [Reaction:R-DRE-5082387] Phosphorylation of HSF1 at Ser230 induces transactivation - Danio rerio [BlackBoxEvent:R-DRE-5082356] HSF1-mediated gene expression - Danio rerio [Pathway:R-DRE-3371568] Attenuation phase - Danio rerio
inferredFrom	[Pathway:R-HSA-3371571] HSF1-dependent transactivation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	HSF1-dependent transactivation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-3371571
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-3371556] Cellular response to heat stress
(inferredTo)	[Pathway:R-HSA-3371571] HSF1-dependent transactivation

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