Reactome | GRB2:SOS1:HB-EGF:p-6Y-EGFR [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10602999] guanyl-nucleotide exchange factor activity of GRB2:SOS1:HB-EGF:p-6Y-EGFR [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10602998
displayName	GRB2:SOS1:HB-EGF:p-6Y-EGFR [plasma membrane]
hasComponent	[Complex:R-DRE-109797] GRB2-1:SOS1 [cytosol] [Complex:R-DRE-2179410] HB-EGF:p-6Y-EGFR dimer [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-2179409] GRB2:SOS1:HB-EGF:p-6Y-EGFR [plasma membrane] - Homo sapiens
maxDepth	4
memberOf	[DefinedSet:R-DRE-5672601] RAS GEFs [plasma membrane] - Danio rerio
name	GRB2:SOS1:HB-EGF:p-6Y-EGFR
producedByEvent	[Reaction:R-DRE-2179415] GRB2:SOS1 binds to HBEGF:p-Y-EGFR - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-2179409
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10602999] guanyl-nucleotide exchange factor activity of GRB2:SOS1:HB-EGF:p-6Y-EGFR [plasma membrane]
(output)	[Reaction:R-DRE-2179415] GRB2:SOS1 binds to HBEGF:p-Y-EGFR
(hasMember)	[DefinedSet:R-DRE-5672601] RAS GEFs [plasma membrane]
(inferredTo)	[Complex:R-HSA-2179409] GRB2:SOS1:HB-EGF:p-6Y-EGFR [plasma membrane]

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