Reactome | Arachidonate is converted to HXA3/B3 by ALOX12

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Arachidonate is converted to HXA3/B3 by ALOX12 Show undefined attributes

catalystActivity	[CatalystActivity:10602666] hydroperoxy icosatetraenoate isomerase activity of ALOX12:Fe2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10602668
displayName	Arachidonate is converted to HXA3/B3 by ALOX12
eventOf	[Pathway:R-DRE-2142696] Synthesis of Hepoxilins (HX) and Trioxilins (TrX) - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2161794] Arachidonate is converted to HXA3/B3 by ALOX12 - Homo sapiens
input	[SimpleEntity:R-ALL-29768] AA [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Arachidonate is converted to HXA3/B3 by ALOX12
output	[DefinedSet:R-ALL-2162031] HXA3/B3 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-2161794
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-2142696] Synthesis of Hepoxilins (HX) and Trioxilins (TrX)
(inferredTo)	[Reaction:R-HSA-2161794] Arachidonate is converted to HXA3/B3 by ALOX12

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