Reactome | VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8

Schema > Reaction > Entries

VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10578033
displayName	VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8
eventOf	[Pathway:R-DRE-216083] Integrin cell surface interactions - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-216076] VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 - Homo sapiens
input	[DefinedSet:R-DRE-4205072] Integrin alphaVbeta3, 5, 8 [plasma membrane] [EntityWithAccessionedSequence:R-DRE-215971] vtnb [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8
output	[Complex:R-DRE-216017] VTN:Integrin alphaVbeta3, 5, 8 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-216076
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-216083] Integrin cell surface interactions
(inferredTo)	[Reaction:R-HSA-216076] VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8

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