Reactome | Iodide is taken up by thyroid epithelial cells

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Iodide is taken up by thyroid epithelial cells Show undefined attributes

catalystActivity	[CatalystActivity:10577249] iodide transmembrane transporter activity of SLC5A5 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10577251
displayName	Iodide is taken up by thyroid epithelial cells
eventOf	[Pathway:R-DRE-209968] Thyroxine biosynthesis - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-209910] Iodide is taken up by thyroid epithelial cells - Homo sapiens
input	[SimpleEntity:R-ALL-209818] I- [extracellular region] 2 × [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Iodide is taken up by thyroid epithelial cells
output	[SimpleEntity:R-ALL-209785] I- [cytosol] 2 × [SimpleEntity:R-ALL-83910] Na+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-209910
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-209968] Thyroxine biosynthesis
(inferredTo)	[Reaction:R-HSA-209910] Iodide is taken up by thyroid epithelial cells

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