Reactome | mature NGF homodimer:p75NTR [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-DRE-205100] NGF ligand:p75NTR:NRIF [plasma membrane] - Danio rerio [Complex:R-DRE-209578] NGF:p75NTR:RIP2 [plasma membrane] - Danio rerio [Complex:R-DRE-209565] NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:Phospho-IKK-beta [plasma membrane] - Danio rerio
consumedByEvent	[Reaction:R-DRE-193656] p75NTR interacts with RIP2 - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10573568
displayName	mature NGF homodimer:p75NTR [plasma membrane]
hasComponent	[Complex:R-DRE-187031] mature beta-NGF homodimer [extracellular region] [EntityWithAccessionedSequence:R-DRE-193664] ngfrb [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-205123] mature NGF homodimer:p75NTR [plasma membrane] - Homo sapiens
maxDepth	3
name	mature NGF homodimer:p75NTR
producedByEvent	[Reaction:R-DRE-193653] NGF homodimer binds to p75NTR - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-205123
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-DRE-209565] NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:Phospho-IKK-beta [plasma membrane] [Complex:R-DRE-209542] NGF ligand:p75NTR:Phospho-IRAK1:polyubiquitinated TRAF6:p62 [plasma membrane] [Complex:R-DRE-209578] NGF:p75NTR:RIP2 [plasma membrane] [Complex:R-DRE-209569] NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] [Complex:R-DRE-209572] NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] [Complex:R-DRE-205100] NGF ligand:p75NTR:NRIF [plasma membrane]
(input)	[Reaction:R-DRE-193656] p75NTR interacts with RIP2
(inferredTo)	[Complex:R-HSA-205123] mature NGF homodimer:p75NTR [plasma membrane]
(output)	[Reaction:R-DRE-193653] NGF homodimer binds to p75NTR