Reactome | NFG and proNGF binds to p75NTR

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10648576
displayName	NFG and proNGF binds to p75NTR
eventOf	[Pathway:R-DRE-193704] p75 NTR receptor-mediated signalling - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:182] neurotrophin TRK receptor signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-193653] NGF homodimer binds to p75NTR - Danio rerio
inferredFrom	[Pathway:R-HSA-205017] NFG and proNGF binds to p75NTR - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	NFG and proNGF binds to p75NTR
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-205017
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-193704] p75 NTR receptor-mediated signalling
(inferredTo)	[Pathway:R-HSA-205017] NFG and proNGF binds to p75NTR

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