Reactome | CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains

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CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains Show undefined attributes

catalystActivity	[CatalystActivity:10599315] chondroitin 6-sulfotransferase activity of CHST3,7 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10599317
displayName	CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains
eventOf	[Pathway:R-DRE-2022870] CS-GAG biosynthesis - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-DRE-2022911] CSPG is secreted - Danio rerio
inferredFrom	[Reaction:R-HSA-2018682] CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains - Homo sapiens
input	[DefinedSet:R-DRE-2064075] chondroitin(3)-core proteins [Golgi lumen] [SimpleEntity:R-ALL-741440] PAPS [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains Chondroitin can be sulfated on position 6 of GalNAc by CHST3,7
output	[DefinedSet:R-DRE-2064219] C6S-PG [Golgi lumen] [SimpleEntity:R-ALL-425969] H+ [Golgi lumen] [SimpleEntity:R-ALL-742343] PAP [Golgi lumen]
precedingEvent	[Reaction:R-DRE-1971487] Chondroitin polymerase complex transfers GalNAc to CS chain - Danio rerio [Reaction:R-DRE-9632033] CSGALNACTs transfer GalNAc to CS chain - Danio rerio [Reaction:R-DRE-741449] SLC35B2,3 exchange cytosolic PAPS with Golgi PAP - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-2018682
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-2022870] CS-GAG biosynthesis
(precedingEvent)	[BlackBoxEvent:R-DRE-2022911] CSPG is secreted
(inferredTo)	[Reaction:R-HSA-2018682] CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains

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