Reactome | COASY transfers an adenylyl group from ATP to PPANT

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COASY transfers an adenylyl group from ATP to PPANT Show undefined attributes

catalystActivity	[CatalystActivity:10574220] pantetheine-phosphate adenylyltransferase activity of COASY [mitochondrial outer membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10574222
displayName	COASY transfers an adenylyl group from ATP to PPANT
eventOf	[Pathway:R-DRE-196783] Coenzyme A biosynthesis - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-9837337] DCAKD phosphorylates DP-CoA - Danio rerio [Reaction:R-DRE-196773] COASY phosphorylates DP-CoA - Danio rerio
inferredFrom	[Reaction:R-HSA-196754] COASY transfers an adenylyl group from ATP to PPANT - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-196767] PPANT [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	COASY transfers an adenylyl group from ATP to PPANT (R)-4'-phosphopantetheine + ATP + H(+) => 3'-dephospho-CoA + diphosphate Adenylation of phosphopantetheine
output	[SimpleEntity:R-ALL-196778] DP-CoA [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
precedingEvent	[Reaction:R-DRE-196840] 3xPPCDC:3FMN decarboxylates PPC - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-196754
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-196783] Coenzyme A biosynthesis
(precedingEvent)	[Reaction:R-DRE-9837337] DCAKD phosphorylates DP-CoA [Reaction:R-DRE-196773] COASY phosphorylates DP-CoA
(inferredTo)	[Reaction:R-HSA-196754] COASY transfers an adenylyl group from ATP to PPANT

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