Reactome | Neuropilin interactions with VEGF and VEGFR

Schema > Pathway > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10648602
displayName	Neuropilin interactions with VEGF and VEGFR
eventOf	[Pathway:R-DRE-194138] Signaling by VEGF - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-195408] NRP-1 forms a ternary complex with VEGF165 and VEGFR1 - Danio rerio [Reaction:R-DRE-195418] NRP-2 associates with VEGFR1 forming complexes on cell surface - Danio rerio
inferredFrom	[Pathway:R-HSA-194306] Neuropilin interactions with VEGF and VEGFR - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Neuropilin interactions with VEGF and VEGFR
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-194306
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-194138] Signaling by VEGF
(inferredTo)	[Pathway:R-HSA-194306] Neuropilin interactions with VEGF and VEGFR

Cite Us!