Reactome | Part of the ICD migrates to the nucleus

Schema > Reaction > Entries

category	transition
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10573742
displayName	Part of the ICD migrates to the nucleus
eventOf	[Pathway:R-DRE-193692] Regulated proteolysis of p75NTR - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-193702] Part of the ICD migrates to the nucleus - Homo sapiens
input	[EntityWithAccessionedSequence:R-DRE-194458] ngfrb [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Part of the ICD migrates to the nucleus
output	[EntityWithAccessionedSequence:R-DRE-197473] ngfrb [nucleoplasm]
precedingEvent	[Reaction:R-DRE-193682] gamma-secretase cleaves the p75NTR transmembrane domain - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-193702
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-193692] Regulated proteolysis of p75NTR
(inferredTo)	[Reaction:R-HSA-193702] Part of the ICD migrates to the nucleus

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