Reactome | Cellular hexose transport

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Cellular hexose transport Show undefined attributes

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10648466
displayName	Cellular hexose transport
eventOf	[Pathway:R-DRE-425407] SLC-mediated transmembrane transport - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:20541] hexose transmembrane transport
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DRE-5339524] GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol - Danio rerio [Reaction:R-DRE-450088] GLUT1 tetramer binds 4xATP - Danio rerio [Reaction:R-DRE-450092] GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP - Danio rerio [Reaction:R-DRE-8981574] GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol - Danio rerio [Reaction:R-DRE-450095] GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region - Danio rerio [Reaction:R-DRE-8981564] GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol - Danio rerio [Reaction:R-DRE-429094] SLC2A6,8,10,12 transport Glc from extracellular region to cytosol - Danio rerio [Reaction:R-DRE-8981553] GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol - Danio rerio [Reaction:R-DRE-189208] SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol - Danio rerio [Reaction:R-DRE-9728150] SLC5A2 binds gliflozins - Danio rerio [Reaction:R-DRE-8876283] SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol - Danio rerio [Reaction:R-DRE-8875902] SLC45A3 transports Glc from extracellular region to cytosol - Danio rerio [Reaction:R-DRE-8876319] SLC50A1 transports Glc from cytosol to extracellular region - Danio rerio [Reaction:R-DRE-429613] SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol - Danio rerio [Reaction:R-DRE-429567] Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 - Danio rerio
inferredFrom	[Pathway:R-HSA-189200] Cellular hexose transport - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Cellular hexose transport
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-189200
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-425407] SLC-mediated transmembrane transport
(inferredTo)	[Pathway:R-HSA-189200] Cellular hexose transport

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