Reactome | CCNA:p-T160-CDK2 [nucleoplasm]

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CCNA:p-T160-CDK2 [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:10560317] cyclin-dependent protein serine/threonine kinase activity of CCNA:p-T160-CDK2 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DRE-187944] CCNA:p-T160-CDK2:p-E2F1/p-E2F3 [nucleoplasm] - Danio rerio [Complex:R-DRE-187932] CCNA:p-T160-CDK2:E2F1/E2F3 [nucleoplasm] - Danio rerio
consumedByEvent	[Reaction:R-DRE-3788708] CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 - Danio rerio [Reaction:R-DRE-187937] Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 - Danio rerio [Reaction:R-DRE-188371] Association of Cyclin A:Cdk2 with Cdh1 - Danio rerio [Reaction:R-DRE-5684081] MRN complex binds CDK2 and RBBP8 - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10560316
displayName	CCNA:p-T160-CDK2 [nucleoplasm]
hasComponent	[CandidateSet:R-DRE-75202] CCNA [nucleoplasm] [EntityWithAccessionedSequence:R-DRE-187967] phospho-p-T160-CDK2 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-187952] CCNA:p-T160-CDK2 [nucleoplasm] - Homo sapiens
maxDepth	3
memberOf	[DefinedSet:R-DRE-8848491] CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] - Danio rerio [DefinedSet:R-DRE-4088020] CCNA:p-CDK1/2 [nucleoplasm] - Danio rerio
name	CCNA:p-T160-CDK2
producedByEvent	[Reaction:R-DRE-5684096] CDK2 phosphorylates RBBP8 - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-187952
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-DRE-3788708] CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 [Reaction:R-DRE-187937] Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 [Reaction:R-DRE-188371] Association of Cyclin A:Cdk2 with Cdh1 [Reaction:R-DRE-5684081] MRN complex binds CDK2 and RBBP8
(physicalEntity)	[CatalystActivity:10560317] cyclin-dependent protein serine/threonine kinase activity of CCNA:p-T160-CDK2 [nucleoplasm]
(hasComponent)	[Complex:R-DRE-187944] CCNA:p-T160-CDK2:p-E2F1/p-E2F3 [nucleoplasm] [Complex:R-DRE-187932] CCNA:p-T160-CDK2:E2F1/E2F3 [nucleoplasm] [Complex:R-DRE-188387] Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] [Complex:R-DRE-188374] Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] [Complex:R-DRE-5684094] DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm]
(hasMember)	[DefinedSet:R-DRE-8848491] CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] [DefinedSet:R-DRE-4088020] CCNA:p-CDK1/2 [nucleoplasm]
(output)	[Reaction:R-DRE-5684096] CDK2 phosphorylates RBBP8
(activeUnit)	[CatalystActivity:10617046] protein serine/threonine kinase activity of DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm]
(inferredTo)	[Complex:R-HSA-187952] CCNA:p-T160-CDK2 [nucleoplasm]

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