Reactome | 5-PP-IP5 transports from the nucleus to the cytosol

Schema > Reaction > Entries

5-PP-IP5 transports from the nucleus to the cytosol Show undefined attributes

catalystActivity	[CatalystActivity:10597876] narrow pore channel activity of Nuclear Pore Complex (NPC) [nuclear envelope]
category	transition
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10597990
displayName	5-PP-IP5 transports from the nucleus to the cytosol
eventOf	[Pathway:R-DRE-1855170] IPs transport between nucleus and cytosol - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-1855158] 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol - Danio rerio [Reaction:R-DRE-1855198] 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol - Danio rerio
goBiologicalProcess	[GO_BiologicalProcess:160102] nuclear export
inferredFrom	[Reaction:R-HSA-1855203] 5-PP-IP5 transports from the nucleus to the cytosol - Homo sapiens
input	[SimpleEntity:R-ALL-2023940] 5-PP-IP5 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	5-PP-IP5 transports from the nucleus to the cytosol
output	[SimpleEntity:R-ALL-1629765] 5-PP-IP5 [cytosol]
precedingEvent	[Reaction:R-DRE-1855207] IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-1855203
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-1855170] IPs transport between nucleus and cytosol
(precedingEvent)	[Reaction:R-DRE-1855158] 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol [Reaction:R-DRE-1855198] 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol
(inferredTo)	[Reaction:R-HSA-1855203] 5-PP-IP5 transports from the nucleus to the cytosol

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