Reactome | SRP-dependent cotranslational protein targeting to membrane

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SRP-dependent cotranslational protein targeting to membrane Show undefined attributes

compartment	[Compartment:70101] cytosol [Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10649572
displayName	SRP-dependent cotranslational protein targeting to membrane
eventOf	[Pathway:R-DRE-72766] Translation - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:20344] SRP-dependent cotranslational protein targeting to membrane
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DRE-1799332] Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) - Danio rerio
inferredFrom	[Pathway:R-HSA-1799339] SRP-dependent cotranslational protein targeting to membrane - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	SRP-dependent cotranslational protein targeting to membrane
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-1799339
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-72766] Translation
(inferredTo)	[Pathway:R-HSA-1799339] SRP-dependent cotranslational protein targeting to membrane

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