Reactome | Unwinding of DNA

Schema > Pathway > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10648420
displayName	Unwinding of DNA
eventOf	[Pathway:R-DRE-69190] DNA strand elongation - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-DRE-69109] Leading Strand Synthesis - Danio rerio [Pathway:R-DRE-69186] Lagging Strand Synthesis - Danio rerio
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-176956] Formation of GINS complex - Danio rerio
inferredFrom	[Pathway:R-HSA-176974] Unwinding of DNA - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Unwinding of DNA
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-176974
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-69190] DNA strand elongation
(precedingEvent)	[Pathway:R-DRE-69109] Leading Strand Synthesis [Pathway:R-DRE-69186] Lagging Strand Synthesis
(inferredTo)	[Pathway:R-HSA-176974] Unwinding of DNA

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