Reactome | SULTs transfer (SO4)2- group to 27HCHOL

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SULTs transfer (SO4)2- group to 27HCHOL Show undefined attributes

catalystActivity	[CatalystActivity:10572053] alcohol sulfotransferase activity of SULTs active on 27HCHOL [cytosol]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10572055
displayName	SULTs transfer (SO4)2- group to 27HCHOL
eventOf	[Pathway:R-DRE-156584] Cytosolic sulfonation of small molecules - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate - Danio rerio
inferredFrom	[Reaction:R-HSA-176494] SULTs transfer (SO4)2- group to 27HCHOL - Homo sapiens
input	[SimpleEntity:R-ALL-176617] 27HCHOL [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-158471] PAPS [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SULTs transfer (SO4)2- group to 27HCHOL 27-hydroxycholesterol + PAPS => 27-hydroxycholesterol 3-sulfate + PAP
output	[SimpleEntity:R-ALL-176502] 27HCHOL3S [cytosol] [SimpleEntity:R-ALL-158466] PAP [cytosol]
precedingEvent	[Reaction:R-DRE-174389] PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-176494
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-156584] Cytosolic sulfonation of small molecules
(precedingEvent)	[Reaction:R-DRE-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
(inferredTo)	[Reaction:R-HSA-176494] SULTs transfer (SO4)2- group to 27HCHOL

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