Reactome | Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2

Schema > Reaction > Entries

Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 Show undefined attributes

catalystActivity	[CatalystActivity:10560702] phosphoprotein phosphatase activity of CDC25A [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10571551
displayName	Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2
eventOf	[Pathway:R-DRE-69656] Cyclin A:Cdk2-associated events at S phase entry - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-174110] Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 - Homo sapiens
input	[Complex:R-DRE-187907] CCNA:p-Y15-CDK2 [nucleoplasm] [SimpleEntity:R-ALL-113518] H2O [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2
output	[Complex:R-DRE-141608] CCNA:CDK2 [nucleoplasm] [SimpleEntity:R-ALL-113550] Pi [nucleoplasm]
precedingEvent	[Reaction:R-DRE-174164] Phosphorylation of Cyclin A:Cdk2 at Tyr 15 - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-174110
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-69656] Cyclin A:Cdk2-associated events at S phase entry
(inferredTo)	[Reaction:R-HSA-174110] Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2

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