Reactome | Signaling by NTRKs

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10648256
displayName	Signaling by NTRKs
eventOf	[Pathway:R-DRE-9006934] Signaling by Receptor Tyrosine Kinases - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:182] neurotrophin TRK receptor signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DRE-9036866] Expression and Processing of Neurotrophins - Danio rerio [Pathway:R-DRE-187037] Signaling by NTRK1 (TRKA) - Danio rerio
inferredFrom	[Pathway:R-HSA-166520] Signaling by NTRKs - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	6
name	Signaling by NTRKs Signaling by Neurotrophin Receptors
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-166520
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-9006934] Signaling by Receptor Tyrosine Kinases
(hasEncapsulatedEvent)	[Pathway:R-DRE-1257604] PIP3 activates AKT signaling
(inferredTo)	[Pathway:R-HSA-166520] Signaling by NTRKs

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