Reactome | AMPK inhibits chREBP transcriptional activation activity

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AMPK inhibits chREBP transcriptional activation activity Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10648222
displayName	AMPK inhibits chREBP transcriptional activation activity
eventOf	[Pathway:R-DRE-163685] Integration of energy metabolism - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:11049] regulation of fatty acid biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-8848663] ADIPOQ trimer binds ADIPOR dimers - Danio rerio [Reaction:R-DRE-163664] AMP binds to gamma subunit of AMP kinase heterotrimer - Danio rerio
inferredFrom	[Pathway:R-HSA-163680] AMPK inhibits chREBP transcriptional activation activity - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	AMPK inhibits chREBP transcriptional activation activity
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-163680
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-163685] Integration of energy metabolism
(inferredTo)	[Pathway:R-HSA-163680] AMPK inhibits chREBP transcriptional activation activity

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