Reactome | Synthesis of PA

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Synthesis of PA Show undefined attributes

created	[InstanceEdit:10427439] Wright, Adam, 2024-03-07
dbId	10483553
displayName	Synthesis of PA
eventOf	[Pathway:R-DRE-1483206] Glycerophospholipid biosynthesis - Danio rerio
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:20462] phosphatidic acid biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-75889] DHAP is converted to G3P by GPD1/GPD1L - Danio rerio [Reaction:R-DRE-549112] G3P is acylated to 1-acyl LPA by AGPAT6 - Danio rerio [Reaction:R-DRE-75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT) - Danio rerio [Reaction:R-DRE-1482656] PA is hydrolysed to 1-acyl LPA by PLA2[1] - Danio rerio [Reaction:R-DRE-1482695] G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) - Danio rerio [Reaction:R-DRE-1482604] PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) - Danio rerio [Reaction:R-DRE-6792445] LIPH, I hydrolyse PA to 2-acyl LPA - Danio rerio [Reaction:R-DRE-8954398] PLD6 dimer hydrolyses cardiolipin to PA and PG - Danio rerio [Reaction:R-DRE-1602446] PA is hydrolyzed to 1-acyl LPA by PLA2[15] - Danio rerio [Reaction:R-DRE-8878654] ACP6 hydrolyses MYS-LPA - Danio rerio [Reaction:R-DRE-8878787] ALPI dimer hydrolyses phosphate monoesters - Danio rerio
inferredFrom	[Pathway:R-HSA-1483166] Synthesis of PA - Homo sapiens
isInDisease	false
isInferred	true
name	Synthesis of PA
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-1483166
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-1483206] Glycerophospholipid biosynthesis
(inferredTo)	[Pathway:R-HSA-1483166] Synthesis of PA

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