Reactome | ABC transporters in lipid homeostasis

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ABC transporters in lipid homeostasis Show undefined attributes

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10648830
displayName	ABC transporters in lipid homeostasis
eventOf	[Pathway:R-DRE-382556] ABC-family protein mediated transport - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:1122] lipid transport
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-5683714] ABCA3 transports PC, PG from ER membrane to lamellar body - Danio rerio [Reaction:R-DRE-8848053] ABCA5 transports CHOL from lysosomal lumen to cytosol - Danio rerio [Reaction:R-DRE-382613] PEX-19 docks ABCD1/D2/D3 to peroximal membrane - Danio rerio [Reaction:R-DRE-382575] ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix - Danio rerio [Reaction:R-DRE-266082] ABCG1-mediated transport of intracellular cholesterol to the cell surface - Danio rerio [Reaction:R-DRE-1454928] ABCG4 may mediate cholesterol efflux - Danio rerio
inferredFrom	[Pathway:R-HSA-1369062] ABC transporters in lipid homeostasis - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	ABC transporters in lipid homeostasis
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-1369062
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-382556] ABC-family protein mediated transport
(inferredTo)	[Pathway:R-HSA-1369062] ABC transporters in lipid homeostasis

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