Reactome | Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10566133
displayName	Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane]
hasComponent	2 × [EntityWithAccessionedSequence:R-DRE-189888] fgf19 [extracellular region] 2 × [EntityWithAccessionedSequence:R-DRE-1307932] klb [plasma membrane] 2 × [EntityWithAccessionedSequence:R-DRE-190330] phospho-p-5Y-FGFR4 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-1307958] Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-DRE-5654158] Activated FGFR4 [plasma membrane] - Danio rerio [DefinedSet:R-DRE-190352] Activated FGFR [plasma membrane] - Danio rerio
name	Activated FGFR4 bound to FGF19:BetaKlotho
producedByEvent	[Reaction:R-DRE-1307963] Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-1307958
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasMember)	[DefinedSet:R-DRE-190352] Activated FGFR [plasma membrane] [DefinedSet:R-DRE-5654158] Activated FGFR4 [plasma membrane]
(output)	[Reaction:R-DRE-1307963] Autocatalytic phosphorylation of BetaKlotho-bound FGFR4
(inferredTo)	[Complex:R-HSA-1307958] Activated FGFR4 bound to FGF19:BetaKlotho [plasma membrane]

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