Reactome | SHC1 events in ERBB4 signaling

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10649420
displayName	SHC1 events in ERBB4 signaling
eventOf	[Pathway:R-DRE-1236394] Signaling by ERBB4 - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-1250383] RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 - Danio rerio
inferredFrom	[Pathway:R-HSA-1250347] SHC1 events in ERBB4 signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	SHC1 events in ERBB4 signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-1250347
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-1236394] Signaling by ERBB4
(inferredTo)	[Pathway:R-HSA-1250347] SHC1 events in ERBB4 signaling

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