Reactome | Effects of PIP2 hydrolysis

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10649096
displayName	Effects of PIP2 hydrolysis
eventOf	[Pathway:R-DRE-76002] Platelet activation, signaling and aggregation - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DRE-425861] Activation of Protein Kinase C novel isoforms - Danio rerio [Reaction:R-DRE-426209] DAG activation of TRPC channels - Danio rerio [Pathway:R-DRE-426048] Arachidonate production from DAG - Danio rerio [Reaction:R-DRE-426240] DAG kinase produces phosphatidic acid from DAG - Danio rerio
inferredFrom	[Pathway:R-HSA-114508] Effects of PIP2 hydrolysis - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Effects of PIP2 hydrolysis
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-114508
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-76002] Platelet activation, signaling and aggregation [Pathway:R-DRE-416476] G alpha (q) signalling events
(inferredTo)	[Pathway:R-HSA-114508] Effects of PIP2 hydrolysis