Reactome | Formation of ADAR1 homodimer

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10566713
displayName	Formation of ADAR1 homodimer
eventOf	[Pathway:R-DRE-77042] Formation of editosomes by ADAR proteins - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-75090] Binding of ADAR1 homodimer to dsRNA duplex - Danio rerio
inferredFrom	[Reaction:R-HSA-111237] Formation of ADAR1 homodimer - Homo sapiens
input	2 × [EntityWithAccessionedSequence:R-DRE-53939] adar [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Formation of ADAR1 homodimer
output	[Complex:R-DRE-111236] ADAR1 homodimer [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-111237
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-77042] Formation of editosomes by ADAR proteins
(precedingEvent)	[Reaction:R-DRE-75090] Binding of ADAR1 homodimer to dsRNA duplex
(inferredTo)	[Reaction:R-HSA-111237] Formation of ADAR1 homodimer

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