Reactome | Cleavage of 3-methyladenine by MPG glycosylase

Schema > Reaction > Entries

Cleavage of 3-methyladenine by MPG glycosylase Show undefined attributes

catalystActivity	[CatalystActivity:10566555] DNA N-glycosylase activity of MPG:3meA-dsDNA [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10566557
displayName	Cleavage of 3-methyladenine by MPG glycosylase
eventOf	[Pathway:R-DRE-110331] Cleavage of the damaged purine - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-110356] Displacement of MPG glycosylase by APEX1 at the AP site - Danio rerio
inferredFrom	[Reaction:R-HSA-110248] Cleavage of 3-methyladenine by MPG glycosylase - Homo sapiens
input	[Complex:R-DRE-110202] MPG:3meA-dsDNA [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Cleavage of 3-methyladenine by MPG glycosylase
output	[SimpleEntity:R-ALL-30947] MADE [nucleoplasm] [Complex:R-DRE-110207] MPG:AP-dsDNA [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-110248
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-DRE-110356] Displacement of MPG glycosylase by APEX1 at the AP site
(hasEvent)	[Pathway:R-DRE-110331] Cleavage of the damaged purine
(inferredTo)	[Reaction:R-HSA-110248] Cleavage of 3-methyladenine by MPG glycosylase

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