Reactome | IL6ST:JAK1, JAK2, (TYK2) [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-DRE-6783658] CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] - Danio rerio
consumedByEvent	[Reaction:R-DRE-6783530] gp130:JAKs bind CNTFR - Danio rerio [Reaction:R-DRE-1067688] IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) - Danio rerio [Reaction:R-DRE-1067651] IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10593039
displayName	IL6ST:JAK1, JAK2, (TYK2) [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-DRE-448453] il6st [plasma membrane] [CandidateSet:R-DRE-1067656] JAK1, JAK2, (TYK2) [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-1067690] IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] - Homo sapiens
maxDepth	3
name	IL6ST:JAK1, JAK2, (TYK2)
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-1067690
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-DRE-6783530] gp130:JAKs bind CNTFR [Reaction:R-DRE-1067688] IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) [Reaction:R-DRE-1067651] IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2)
(hasComponent)	[Complex:R-DRE-6783658] CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] [Complex:R-DRE-1067691] IL6:sIL6R:IL6RB:JAKs [plasma membrane] [Complex:R-DRE-1067654] IL6:IL6RA:IL6RB:JAKs [plasma membrane]
(inferredTo)	[Complex:R-HSA-1067690] IL6ST:JAK1, JAK2, (TYK2) [plasma membrane]