Reactome | NEXT homodimer [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DME-9930062] NEXT:ZC3H18:CBCA:m7GpppN-RNA [nucleoplasm] - Drosophila melanogaster [Complex:R-DME-9934534] RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA [nucleoplasm] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-9930059] The NEXT complex binds ZC3H4:WDR82:CBCA:m7GpppN-RNA - Drosophila melanogaster [Reaction:R-DME-9930056] The NEXT complex and ZC3H18 bind CBCA:m7GpppN-RNA - Drosophila melanogaster
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10909366
displayName	NEXT homodimer [nucleoplasm]
hasComponent	2 × [Complex:R-DME-8985567] RBM7:ZCCHC8:SKIV2L2 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-9935998] NEXT homodimer [nucleoplasm] - Homo sapiens
maxDepth	3
name	NEXT homodimer
producedByEvent	[BlackBoxEvent:R-DME-9934763] The RNA exosome in RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA hydrolyzes RNA - Drosophila melanogaster [BlackBoxEvent:R-DME-9935290] The RNA exosome in RNA exosome:NEXT:ZC3H4:WDR82:CBCA:capped RNA hydrolyzes capped RNA - Drosophila melanogaster
schemaClass	Complex
species	[Species:56210] Drosophila melanogaster
stId	R-DME-9935998
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[BlackBoxEvent:R-DME-9934763] The RNA exosome in RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA hydrolyzes RNA [BlackBoxEvent:R-DME-9935290] The RNA exosome in RNA exosome:NEXT:ZC3H4:WDR82:CBCA:capped RNA hydrolyzes capped RNA
(input)	[Reaction:R-DME-9930056] The NEXT complex and ZC3H18 bind CBCA:m7GpppN-RNA [Reaction:R-DME-9930059] The NEXT complex binds ZC3H4:WDR82:CBCA:m7GpppN-RNA
(hasComponent)	[Complex:R-DME-9934534] RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA [nucleoplasm] [Complex:R-DME-9930062] NEXT:ZC3H18:CBCA:m7GpppN-RNA [nucleoplasm] [Complex:R-DME-9935306] RNA exosome:NEXT:ZC3H4:CBCA:m7GpppN-RNA [nucleoplasm] [Complex:R-DME-9930060] NEXT:ZC3H4:CBCA:m7GpppN-RNA [nucleoplasm]
(inferredTo)	[Complex:R-HSA-9935998] NEXT homodimer [nucleoplasm]

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